New technologies could make it possible to bring extinct species back to life, concludes a paper published on April 4 in the journal Science. These advances include back-breeding (assembling or reassembling an extinct species' genes), cloning and genetic engineering. Woolly Mammoth
A leading candidate for de-extinction is the woolly mammoth. Russian scientist Semyon Grigoriev, of the Sakha Republic's mammoth museum, plans to replace the nuclei of an elephant egg with nuclei extracted from woolly mammoth bone marrow. The elephant would theoretically become a surrogate mother to a baby mammoth.
Tasmanian TigerTasmanian tigers died out in 1936, in part because they had little genetic diversity which translates to "bad news for a species," said Katherine Belov, professor of comparative genomics at the University of Sydney. "Species are less able to adapt to change." Even if Tasmanian tigers -- or other animals -- are resurrected, it will take some time to build up diversity again.
Passenger Pigeon Experts believe billions of these birds populated the Americas when Europeans arrived. Loss of habitat and commercial exploitation of the birds for their meat are thought to have killed them all off. Efforts are now underway to revive the species by extracting DNA fragments from preserved specimens, and later, using band-tailed pigeons as surrogate parents.
Pyrenean Ibex The Pyrenean ibex, a horned mammal once common in Europe, was one of the first subspecies targeted for de-extinction. Scientists began the attempts in late 1990s, when the last female Pyrenean ibex was still alive. Even if researchers could successfully clone that individual, there would be no males for her to breed with. Instead, genetic engineering might be required
Saber-toothed Cat Since saber-toothed cat bodies are sometimes found frozen, it might be possible to extract preserved DNA and clone the animal. About 5 years ago, scientists did just that with a mouse that was dead and frozen for 16 years. Woolly mammoth remains are also sometimes found in a well-preserved, frozen state.
Dodo Bird The dodo, a flightless bird, proved to be a tasty meal for humans and other predators. In 2007, scientists found a remarkably well-preserved dodo in a cave. Dodo DNA could be used to resurrect this avian species.
Ground Sloth Ground sloths, relatively slow, lumbering animals, were easy targets for prehistoric big-game hunters. Scientists have found remains that still bear soft tissue. As with woolly mammoths, there's a chance extracted DNA could be used to back-breed or clone the large sloths.
Irish Elk The Irish elk has been extinct for 11,000 years. Like the woolly mammoth, it inhabited colder regions. As a result, bodies are sometimes found frozen and in relatively good condition, making them candidates for DNA extraction.
Neanderthal Earlier this year, Harvard geneticist George Church -- with tongue in cheek -- said that he was seeing an "adventurous female human" to be a surrogate mother to a cloned Neanderthal. While Church was really just theorizing about what it would take to bring a Neanderthal back to life, the possibility could be a reality, should any scientist undertake such a controversial project.
Dinosaur Paleontologist Jack Horner is leading a project to create a dinosaur out of a chicken -- a "dinochicken." He told Discovery News that birds "are dinosaurs, so technically we're making a dinosaur out of a dinosaur." He and his colleagues have been genetically engineering chickens to reactivate ancestral traits, such as long tails, which are more associated with non-avian dinosaurs.
