The word mathematics comes from the Greek μάθημα (máthēma), which, in the ancient Greek language, means "that which is learnt",^[24] "what one gets to know", hence also "study" and "science", and in modern Greek just "lesson". The word máthēma is derived from μανθάνω (manthano), while the modern Greek equivalent is μαθαίνω (mathaino), both of which mean "to learn". In Greece, the word for "mathematics" came to have the narrower and more technical meaning "mathematical study" even in Classical times.^[25] Its adjective is μαθηματικός (mathēmatikós), meaning "related to learning" or "studious", which likewise further came to mean "mathematical". In particular, μαθηματικὴ τέχνη (mathēmatikḗ tékhnē), Latin: ars mathematica, meant "the mathematical art".

In Latin, and in English until around 1700, the term mathematics more commonly meant "astrology" (or sometimes "astronomy") rather than "mathematics"; the meaning gradually changed to its present one from about 1500 to 1800. This has resulted in several mistranslations: a particularly notorious one is Saint Augustine's warning that Christians should beware of mathematici meaning astrologers, which is sometimes mistranslated as a condemnation of mathematicians.^[26]

The apparent plural form in English, like the French plural form les mathématiques (and the less commonly used singular derivative la mathématique), goes back to the Latin neuter plural mathematica (Cicero), based on the Greek plural τα μαθηματικά (ta mathēmatiká), used by Aristotle (384–322 BC), and meaning roughly "all things mathematical"; although it is plausible that English borrowed only the adjective mathematic(al) and formed the noun mathematics anew, after the pattern of physics and metaphysics, which were inherited from the Greek.^[27] In English, the noun mathematics takes singular verb forms. It is often shortened to maths or, in English-speaking North America, math.^[28]