Infertility is the main challenge of 21st century in  human life and almost one third of the infertilities are caused by a male factor.Various conditions can interfere with spermatogenesis and minimize  both sperm  quality and sperm production. Other factors like  drug  treatment,air pollution, chemotherapy, toxins,  and insufficient vitamins intake have negative impact on spermatogenesis and sperm normal production.Recent researches have showed that antioxidants and vitamin A, B, C, and E in diet can protect  sperm DNA from free radicals and boost blood  testis barrier stability. Right now ginger  rhizome  or Zingiber officinale R., family:  Zingiberaceae, is used worldwide as an ingredient for spice reciepe.Antioxidative and androgenic activity  of Z.  officinale were known in animal models.

The main active ingredients of Z. officinale, such related studies showed that ginger oil has  dominative protective effect on DNA damage induced by H2O2 and might act as a scavenger and as an antioxidant . Antioxidants protect DNA and related molecules from oxidation and damage, and can  improve sperm quality and consequently maximize fertility level in men .That's why the role of nutritional and biochemical factors in reproduction and subfertility treatment is very important. Different discriminating couples suffering from infertility are seeking natural solutions to  maximize fertility.

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