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I love these two! The chemistry of Reese Witherspoon and Sofia Vergara in person is as palpable as their chemistry on-screen for their new road trip buddy comedy “Hot Pursuit!” In this interview, we talked about how they developed their chemistry, working with director Anne Fletcher, why Witherspoon followed up his Oscar-nominated role in “Wild” with a comedy, the infamous “lesbian” kiss, and their humanitarian efforts in helping make the world a better place to live.